Children and Families Policy Research Unit awarded £5.5m by NIHR

Children and Families Policy Research Unit awarded £5.5m by NIHR

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Children and Families Policy Research Unit awarded £5.5m by NIHR

The Children and Families Policy Research Unit (CPRU) has been awarded funding worth an estimated £5.5M by the National Institute of Health and Care Research (NIHR), to continue its operations for the next five years, starting from January 2024. Dr Johnny Downs, an NIHR Clinician Scientist at the IoPPN, King’s College London, has been named a co-investigator of the CPRU.

The CPRU is a collaboration between UCL and the universities of Bristol, Oxford, Manchester, Newcastle, King’s College London, Bradford Institute for Health Research, Anna Freud Centre, and Institute of Fiscal Studies. The aim of the CPRU is to conduct high-quality research which enables policymakers and practitioners to make informed decisions which affect the nation’s health and wellbeing. The announcement builds on the work done by the CPRU over a decade, and further strengthens its commitment to support evidence based policy-making at a local and national level.

Under the co-directorship of Professor Ruth Gilbert, GOS Institute of Child Health, Institute of Education, and Dr Jenny Woodman, Institute of Education (IOE), Social Research Institute, and Thomas Coram Research Institute, the CPRU has worked to deliver groundbreaking research programmes into addressing health inequalities, supporting vulnerable children and families, and improving health outcomes for children with disabilities and long-term conditions. The CPRU works closely with children and families to put their experiences at the heart of research and ensure that they can inform and influence policy decisions.

Dr Jenny Woodman said: “With this important funding, we will be able to work with analysts and policy colleagues at the Department of Health and Social Care and other government departments to generate and present high quality evidence at the right time to support their decisions. We research what makes children healthier, taking into account the environments in which they live, the places they spend time, the health of their parents and carers and siblings and the health, education and other services they and their families use.”

 

It is a great privilege to join the NIHR Children and Families Policy Research Unit at UCL which has such a wonderful track history in creating data resources, developing research methods and delivering high quality evidence that impacts policy and practice for children and families. Between 2024-2029, the policy research programme will be examining how public, primary and specialist physical and mental health interventions can best deliver effective health and social care for vulnerable children and families and reduce health disparities. The Unit has put together a great interdisciplinary team and I am delighted that its work has such a strong emphasis on engaging young people, their families, mental health clinicians and researchers. I’m really looking forward to getting started.
Dr Johnny Downs

NIHR Clinician Scientist at the Department of Child & Adolescent Psychiatry at King's IoPPN and co-investigator on the NIHR Children and Families Policy Research Unit

The funding will enable a further five years of research on priority policy areas for child and family health for the Department of Health and Social Care, such as health inequalities, early years support for children and parents, support from health, education and social care for children and young people affected by chronic physical or mental health conditions, and services to address family violence.

The award is part of a package of funding for Policy Research Units across England & Wales announced by NIHR worth an estimated £100M.

 

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New parenting app reduced child emotional difficulties during COVID-19 pandemic

New parenting app reduced child emotional difficulties during COVID-19 pandemic

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New parenting app reduced child emotional difficulties during COVID-19 pandemic

New research finds a novel parenting smartphone app, developed by researchers at the Institute of Psychiatry, Psychology & Neuroscience (IoPPN) at King’s College London and South London and Maudsley NHS Foundation Trust, reduced child emotional problems during the COVID-19 pandemic.

Published in the Journal of Medical Internet Research (JMIR), the Supporting Parents And Kids Through Lockdown Experiences (SPARKLE) trial – a collaboration between King’s and the University of Oxford – investigated whether Parent Positive was effective in reducing child emotional and conduct problems and improving parents’ own wellbeing, and whether improvements were achieved in a cost-effective way.

Researchers followed 646 parents with children aged between four and 10 between May and July 2021, with 320 receiving access to Parent Positive compared with 326 who did not. They found that Parent Positive reduced child emotional problems after both one and two months of access to the app, compared to not having app access at all. This was found to be a cost-effective way of reducing children’s emotional problems.

We believe our study is the first clinical trial of a parenting support app designed specifically to support parents during the COVID-19 pandemic. In response to the pandemic and subsequent lockdowns, we quickly developed Parent Positive to help mitigate the impact on children’s emotional and conduct problems. We found that, on average, families who had access to the app reported reduced child emotional problems compared to those who did not. The findings highlight that, if implemented across the general UK population, Parent Positive could have the potential to make a significant contribution to reducing child emotional problems.

Dr Melanie Palmer

Postdoctoral Research Associate at King’s IoPPN and first author of the JMIR article

The COVID-19 lockdowns presented parents with some extraordinary challenges. Getting face-to-face support to them using traditional approaches was very challenging during this period. The results from the SPARKLE trial highlight the potential of digital approaches as a way of disseminating advice and support to parents that can produce tangible results. We are hopeful that this approach can have many uses in the post-COVID world in providing a resource to families in underserved or marginalised communities or utilised as part of first-line interventions in hard pressed services.

Professor Edmund Sonuga-Barke

Professor of Developmental Psychology, Psychiatry & Neuroscience at King’s IoPPN and Principal Investigator on SPARKLE

Contrary to the researchers’ expectations, access to the app did not lead to significant improvements in child conduct problems, despite the advice on managing difficult behaviours it provided. Researchers also found no evidence that those who had access to the app experienced less parent psychological distress, parental child-related worries, or family conflict than those who did not. In fact, there was an increase in child-related parental worries after two-months. The researchers explain that this may be due to the difficulties related to changing parenting styles and routines, or the increase in awareness of good parenting practices leading to insecurity about their parenting skills.

The researchers collaborated with parents of young children across all aspects of the study to better understand their views on how the app could address their support needs. They are now co-developing the app further to improve usability, increase engagement and improve the positive effects for parents and their children.

SPARKLE was funded by the UK Research and Innovation Economic and Social Research Council (UKRI-ESRC).

‘The effectiveness of a universal digital parenting intervention designed and implemented during the COVID-19 pandemic: Evidence from a rapid implementation randomised controlled trial within a cohort’ (Melanie Palmer, Nicholas Beckley-Hoelscher, James Shearer, Katarzyna Kostyrka-Allchorne, Olly Robertson, Marta Koch, Oliver Pearson, Petr Slovak, Crispin Day, Sarah Byford, Kimberley Goldsmith, Polly Waite, Cathy Creswell & Edmund J S Sonuga-Barke) was published in the Journal of Medical Internet Research (DOI: 10.2196/44079).

For more information, please contact Amelia Remmington (Communications & Engagement Officer).

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King’s College London receives £11m Research England grant to transform research into children and young people’s mental health

King’s College London receives £11m Research England grant to transform research into children and young people’s mental health

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King’s College London receives £11m Research England grant to transform research into children and young people’s mental health
Over £11m of funding from UK Research Partnership Investment Fund (UKRPIF) for King’s College London from Research England will fund cutting-edge brain imaging equipment and a pioneering mental health research collaboration hub at the Pears Maudsley Centre for Children and Young People, which will open in South London in 2024.

The new clinical research Centre will be the only facility in Europe whose primary focus is on mental disorders and neurodevelopmental conditions affecting children and young people.

This equipment will provide a significant upgrade to the Centre’s research capabilities, transforming understanding of the interplay between young brains, behaviour and cognition, by providing cutting-edge clinical research equipment alongside a dedicated research collaboration hub, and facilitating collaboration with all sectors across the UK. Researchers will be able to work alongside the young patients and families who are being supported by clinical services in the Pears Maudsley Centre to improve their understanding of why children develop these conditions and how treatments work and deliver more effective prevention strategies.

The Pears Maudsley Centre is home to the King’s Maudsley Partnership – comprising King’s College London, South London and Maudsley NHS Foundation Trust and the Maudsley Charity.

Children’s brains, thinking styles and experience of the world are not the same as adults. This exciting news means that we can get the necessary equipment to undertake the cutting-edge research required to improve children and young people’s mental health. This new funding means we can better understand the specific disorder mechanisms underpinning mental health problems and identify and test opportunities for effective intervention.
Professor Emily Simonoff

Interim Director of the King's Maudsley Partnership

Professor Dame Jessica Corner, Executive Chair at Research England, said: “I am delighted that we are able to support The Pears Maudsley Centre with £11m from the UKRPIF fund. The investment will enable King’s College London to develop an invaluable collaborative research environment in which to drive the creation of personalised mental health prevention and treatment strategies for children and young people.

“We hope this funding will help enable new insights into the causes and progression of these disorders which affect one in six young people and provide a transformative leap forward in research in this area by leveraging King’s College London’s unrivalled expertise in the field.”

The state-of-the-art equipment will give new insights and transform understanding of why some children develop mental health problems, allowing researchers to develop effective ways to prevent and treat mental illness both in the UK and around the world. To date, many studies have been carried out with equipment designed for adults or those without neurodevelopmental conditions.

The new equipment is specifically designed for use with babies, children and young people to enable the study of their brain structure and function, cognition and emotions.

It includes:

  • OPM-Magnetoencephalography (MEG) which is worn like a helmet and adapts to any head size, including babies, allowing participants to move freely, play or interact with family during a scan. The MEG cap tracks brain networks in real time and can be an early indicator of conditions such as autism or ADHD.
  • 3T MRI (Magnetic Resonance Imaging) a high-quality portable MRI which is well-suited to children.
  • Child friendly suites for near infra-red (NIRS) and electroencephalography (EEG) and eye-tracking which are more robust for younger children and those who find it difficult to sit still.
  • Immersive assessment facility (to understand social and cognitive function in real world settings) and VR for both experiences and therapy.

Despite the urgency and scale of the challenge, mental health research lags far behind the focus and discoveries resulting from successful investment in physical health care research. As of 2018, only 6.1% of the UK’s health research budget was spent on mental health and funding has remained largely unchanged for a decade1. As a result, improvements in prevention and care are progressing too slowly to meet the increasing need.
This investment from Research England will support a step-change in mental health research for young people.

The ambitions of the Pears Maudsley Centre are to ensure that all young people enter adult life with their best mental health by generating new scientific insights, reducing the time taken to translate new discoveries into effective prevention and treatment effective programmes.

The Pears Maudsley Centre is set to be a game-changer in children and young people’s mental health. This UKRPIF and philanthropic funding will enable us to deliver a major upgrade in research capabilities, by providing cutting-edge clinical research equipment alongside a dedicated research collaboration hub, facilitating collaboration between our world leading academics and clinicians. It will give us a crucial understanding of brain mechanisms and more accurate, personalised measures of treatment in a specialist clinical research facility designed specifically for children and young people.

Professor Shitij Kapur

President & Principal of King’s College London

The funding from Research England is double match-funded (£22m) by private and philanthropic sources, including Maudsley Charity, Pears Foundation, The Rayne Foundation, The Charles Wolfson Charitable Trust, The Wolfson Foundation, Garfield Weston Foundation, and The Prudence Trust.

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£4.5M awarded to South London and Maudsley NHS Foundation Trust for cutting-edge research equipment and technology

£4.5M awarded to South London and Maudsley NHS Foundation Trust for cutting-edge research equipment and technology

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£4.5M awarded to South London and Maudsley NHS Foundation Trust for cutting-edge research equipment and technology

The National Institute for Health and Care Research (NIHR) has awarded more than £4.5 million to South London and Maudsley NHS Foundation Trust to pay for new research equipment and technology.

a young girl holding a leaf

This will be used to improve the accessibility of the Trust’s research so more patients and service users have the opportunity to take part in research. It will include a new sleep laboratory, equipment for the Informatics theme of the NIHR Maudsley Biomedical Research Centre and resources for the new Pears Maudsley Centre for Children and Young People.

New sleep laboratory at the NIHR King’s Clinical Research Facility (CRF)

This investment will allow the creation of a sleep laboratory to study the impact of disturbed sleep on brain functioning and mental health. This will be based in the NIHR King’s Clinical Research Facility and the funding will refurbish existing space for private rooms and purchase new equipment designed for sleep studies. When not used for sleep research, these new facilities will be available as generic clinical space for experimental medicine, thus increasing our capacity for studies across the CRF’s portfolio.

The sleep laboratory will be a leader in this field, building on existing strengths in the development of both silent and motion insensitive MRI, relationships with industry and the UK’s largest clinical sleep service that spans across King’s Health Partners

Pears Maudsley Centre for Children and Young People

The equipment and facilities of the Pears Maudsley Centre for Children and Young People will revolutionize the type and scope of research undertaken, enhancing our understanding of the relationship between brain-based mechanisms, clinical disorders, and social context.

This funding will pay for an MRI compatible EEG system for imaging infants to be used in perinatal services and additional eye tracking equipment that is specifically helpful for younger children who find it difficult to sit still during data capture.

The equipment will enable researchers to explore the interplay between brain and social/environmental risk factors such as trauma exposure, poverty, parental mental illness with an aim to investigate potential prevention targets.

NIHR Maudsley BRC Informatics

The funding will provide dedicated BRC storage and high-performance computing facilities to enable the informatics team to process large datasets. This hardware will enhance research capacity and capability, supporting the development of large language models and increasing the speed of testing of deep learning models. It will also support the creation of a  Mobile Health and Speech Lab which  include a collection of devices and speech equipment to ensure a standardised process for testing, benchmarking, piloting, and evaluating existing and emerging devices for data collection.

“We are delighted that the NIHR has chosen to award £4.5m to South London and Maudsley. It will fund equipment for our new Pears Maudsley Centre for Children and Young People to enable our academics and clinicians to continue their world-leading research into the prevention and treatment of mental illness.”

David Bradley

Chief Executive Officer, South London and Maudsley NHS Foundation Trust

“This investment will allow us to purchase equipment, technology and hardware, across the NIHR Maudsley BRC, NIHR King’s CRF and for the Pears Maudsley Centre. Not only will this enhance our research capacity and capability, it will also improve the experience of participants in research, particularly children and people with mental health conditions, because our facilities have been designed with their needs in mind.  We are delighted that our application was considered excellent by the NIHR committee.”

Professor Matthew Hotopf

CBE FRCPsych FMedSci, Director of the NIHR Maudsley BRC, and Vice Dean (Research), Institute of Psychiatry, Psychology & Neuroscience, King’s College London

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Working with students and teachers to evaluate secondary school stress workshops

Working with students and teachers to evaluate secondary school stress workshops

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Working with students and teachers to evaluate secondary school stress workshops
Dr June Brown is Reader/Associate Professor in Clinical Psychology at the Institute of Psychiatry, Psychology & Neuroscience (IoPPN) at King’s College London and the lead for Brief Educational workshops in Secondary Schools Trial (BESST). In this blog she describes how a small pilot with schools in South London has now led to a national clinical trial funded by the National Institute for Health and Care Research (NIHR) with 900 students across 57 schools.
Dr June Brown

Dr June Brown

Reader/Associate Professor in Clinical Psychology at the Institute of Psychiatry, Psychology & Neuroscience (IoPPN) at King's College London

I have always had a longstanding interest is how we reach people who do not or can not access services for depression and anxiety, especially as evidence suggests only about 30% of people with mental health problems actually receive help and 70% never get the support they need.

To try and rectify this number at a grass roots level I started running workshops for adults in Southwark, in everyday settings such as leisure or community centres. These workshops covered stress, depression/self-confidence, insomnia, and anger. They aimed to be effective as well accessible to the general public who would normally not access help from clinical services.

Key to their accessibility was the use of a self-referral system, so those who felt they needed this help could simply come along to the workshop. We found this approach attracted large numbers of minoritised groups and also those who had not previously sought help from their GPs.

From small beginnings to a national clinical trial

Dr Irene Sclare, a clinical psychologist at South London and Maudsley who works with adolescents, shared my thinking about this need for accessible interventions, especially for young people who encounter significant barriers to help from the NHS because of long waiting lists, inconvenient appointment times and locations (often during school hours and in clinics), and the prioritisation of care for those with very severe problems.

Irene started developing stress workshops for adolescents and, in 2014, we first ran a very small pilot study of the workshops (known as DISCOVER) in schools in South London. We subsequently ran a slightly larger study in 2019 which showed the DISCOVER workshops were accessible and likely to be effective. However, a larger study was needed to rigorously investigate the effectiveness of the workshops.

In July 2019 we received a grant from the NIHR Heath Technology Assessment (HTA) for just under £1.7m to run this clinical trial which covers four regions of England: London, Midlands, Southwest, and Northwest. Our target was to recruit 900 students in 60 schools across these 4 regions – half of which would receive the workshop.

BESST – the trial

When we started the trial in January 2020, we had to pause for a year as lockdown was put in place on 26th March 2020, a week after our trial manager began work! A year later we re-started the trial and recruited our research workers in anticipation of a start in September 2021, despite various scares about schools not letting us in (and maybe even having to change to an online intervention!)

Once we re-started the trial in April 2021 and decided that we would stick to face-to-face workshops, we recruited 19 schools and 6 services to deliver the workshops. We did succeed in recruiting 379 students in September 2021 and then had to work extremely hard the following year to make up the difference. In year 2, we recruited 11 services and 38 schools, enrolling 521 students into the trial.

Now we have reached our target of 900 students across 57 schools and are getting over 90 per cent follow-up rates, which we’re very happy about. A really interesting (and important) finding is that just under half of the students are from diverse backgrounds and that 80 per cent have not previously received help. This demonstrates the key element of accessibility that we hoped to build into these workshops and the research.

What has led to this success? So many things …

The workshop delivery teams have been very enthusiastic about getting trained in our approach. The school staff have also been really keen for the workshops to be offered to their students.

We think we have reached so many students because they believed that they needed the workshops even though they knew there was a 50 per cent chance they wouldn’t receive them. As in those first workshops I ran in Southwark in 2004 I think the self-referral system has really helped in reaching so many students. It has allowed them to feel an element of control about enrolling where they did have the choice, and weren’t required to go through a formalised diagnostic process.

“I think that the study was really helpful when it comes to stress and depression in students….they taught us really useful ways to help deal with that kind of stuff, especially stress about relationships and exams… I think that the best way BESST could help more students is by doing this workshop in more schools, all schools if possible. By offering this experience to everyone would bring more of an awareness to how to deal with mental health problems such as depression and stress.”
Aiden

BESST participant

Alongside this, the collaboration in our team has been brilliant. The BESST trial management team has helped to work through the challenges of the pandemic as well as running this exciting trial. The research workers have also been a fantastic group who have worked really hard to make the trial a success. And last but not least, our trial manager, Steve Lisk, has been superb, empathetically leading the research workers and calmly handling the difficulties that have arisen so we could reach our targets.

The future

We are expecting the results of the trial to be analysed in 2 months’ time, so we are very excited – and a bit anxious – about what we will find!

Whatever the outcome we are extremely grateful for everyone who took part in the research: the delivery teams, the school staff and of course the students. Their commitment to the process and the workshops has been essential to conducting an authentic evaluation across so many schools.

We are now impatiently waiting for the results. If they show the workshops are effective, we could be rolling them out across the whole of the UK which would mean many more students will benefit from this one trial!

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