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King’s College London receives £11m Research England grant to transform research into children and young people’s mental health

King’s College London receives £11m Research England grant to transform research into children and young people’s mental health

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King’s College London receives £11m Research England grant to transform research into children and young people’s mental health
Over £11m of funding from UK Research Partnership Investment Fund (UKRPIF) for King’s College London from Research England will fund cutting-edge brain imaging equipment and a pioneering mental health research collaboration hub at the Pears Maudsley Centre for Children and Young People, which will open in South London in 2024.

The new clinical research Centre will be the only facility in Europe whose primary focus is on mental disorders and neurodevelopmental conditions affecting children and young people.

This equipment will provide a significant upgrade to the Centre’s research capabilities, transforming understanding of the interplay between young brains, behaviour and cognition, by providing cutting-edge clinical research equipment alongside a dedicated research collaboration hub, and facilitating collaboration with all sectors across the UK. Researchers will be able to work alongside the young patients and families who are being supported by clinical services in the Pears Maudsley Centre to improve their understanding of why children develop these conditions and how treatments work and deliver more effective prevention strategies.

The Pears Maudsley Centre is home to the King’s Maudsley Partnership – comprising King’s College London, South London and Maudsley NHS Foundation Trust and the Maudsley Charity.

Children’s brains, thinking styles and experience of the world are not the same as adults. This exciting news means that we can get the necessary equipment to undertake the cutting-edge research required to improve children and young people’s mental health. This new funding means we can better understand the specific disorder mechanisms underpinning mental health problems and identify and test opportunities for effective intervention.
Professor Emily Simonoff

Interim Director of the King's Maudsley Partnership

Professor Dame Jessica Corner, Executive Chair at Research England, said: “I am delighted that we are able to support The Pears Maudsley Centre with £11m from the UKRPIF fund. The investment will enable King’s College London to develop an invaluable collaborative research environment in which to drive the creation of personalised mental health prevention and treatment strategies for children and young people.

“We hope this funding will help enable new insights into the causes and progression of these disorders which affect one in six young people and provide a transformative leap forward in research in this area by leveraging King’s College London’s unrivalled expertise in the field.”

The state-of-the-art equipment will give new insights and transform understanding of why some children develop mental health problems, allowing researchers to develop effective ways to prevent and treat mental illness both in the UK and around the world. To date, many studies have been carried out with equipment designed for adults or those without neurodevelopmental conditions.

The new equipment is specifically designed for use with babies, children and young people to enable the study of their brain structure and function, cognition and emotions.

It includes:

  • OPM-Magnetoencephalography (MEG) which is worn like a helmet and adapts to any head size, including babies, allowing participants to move freely, play or interact with family during a scan. The MEG cap tracks brain networks in real time and can be an early indicator of conditions such as autism or ADHD.
  • 3T MRI (Magnetic Resonance Imaging) a high-quality portable MRI which is well-suited to children.
  • Child friendly suites for near infra-red (NIRS) and electroencephalography (EEG) and eye-tracking which are more robust for younger children and those who find it difficult to sit still.
  • Immersive assessment facility (to understand social and cognitive function in real world settings) and VR for both experiences and therapy.

Despite the urgency and scale of the challenge, mental health research lags far behind the focus and discoveries resulting from successful investment in physical health care research. As of 2018, only 6.1% of the UK’s health research budget was spent on mental health and funding has remained largely unchanged for a decade1. As a result, improvements in prevention and care are progressing too slowly to meet the increasing need.
This investment from Research England will support a step-change in mental health research for young people.

The ambitions of the Pears Maudsley Centre are to ensure that all young people enter adult life with their best mental health by generating new scientific insights, reducing the time taken to translate new discoveries into effective prevention and treatment effective programmes.

The Pears Maudsley Centre is set to be a game-changer in children and young people’s mental health. This UKRPIF and philanthropic funding will enable us to deliver a major upgrade in research capabilities, by providing cutting-edge clinical research equipment alongside a dedicated research collaboration hub, facilitating collaboration between our world leading academics and clinicians. It will give us a crucial understanding of brain mechanisms and more accurate, personalised measures of treatment in a specialist clinical research facility designed specifically for children and young people.

Professor Shitij Kapur

President & Principal of King’s College London

The funding from Research England is double match-funded (£22m) by private and philanthropic sources, including Maudsley Charity, Pears Foundation, The Rayne Foundation, The Charles Wolfson Charitable Trust, The Wolfson Foundation, Garfield Weston Foundation, and The Prudence Trust.

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£4.5M awarded to South London and Maudsley NHS Foundation Trust for cutting-edge research equipment and technology

£4.5M awarded to South London and Maudsley NHS Foundation Trust for cutting-edge research equipment and technology

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£4.5M awarded to South London and Maudsley NHS Foundation Trust for cutting-edge research equipment and technology

The National Institute for Health and Care Research (NIHR) has awarded more than £4.5 million to South London and Maudsley NHS Foundation Trust to pay for new research equipment and technology.

a young girl holding a leaf

This will be used to improve the accessibility of the Trust’s research so more patients and service users have the opportunity to take part in research. It will include a new sleep laboratory, equipment for the Informatics theme of the NIHR Maudsley Biomedical Research Centre and resources for the new Pears Maudsley Centre for Children and Young People.

New sleep laboratory at the NIHR King’s Clinical Research Facility (CRF)

This investment will allow the creation of a sleep laboratory to study the impact of disturbed sleep on brain functioning and mental health. This will be based in the NIHR King’s Clinical Research Facility and the funding will refurbish existing space for private rooms and purchase new equipment designed for sleep studies. When not used for sleep research, these new facilities will be available as generic clinical space for experimental medicine, thus increasing our capacity for studies across the CRF’s portfolio.

The sleep laboratory will be a leader in this field, building on existing strengths in the development of both silent and motion insensitive MRI, relationships with industry and the UK’s largest clinical sleep service that spans across King’s Health Partners

Pears Maudsley Centre for Children and Young People

The equipment and facilities of the Pears Maudsley Centre for Children and Young People will revolutionize the type and scope of research undertaken, enhancing our understanding of the relationship between brain-based mechanisms, clinical disorders, and social context.

This funding will pay for an MRI compatible EEG system for imaging infants to be used in perinatal services and additional eye tracking equipment that is specifically helpful for younger children who find it difficult to sit still during data capture.

The equipment will enable researchers to explore the interplay between brain and social/environmental risk factors such as trauma exposure, poverty, parental mental illness with an aim to investigate potential prevention targets.

NIHR Maudsley BRC Informatics

The funding will provide dedicated BRC storage and high-performance computing facilities to enable the informatics team to process large datasets. This hardware will enhance research capacity and capability, supporting the development of large language models and increasing the speed of testing of deep learning models. It will also support the creation of a  Mobile Health and Speech Lab which  include a collection of devices and speech equipment to ensure a standardised process for testing, benchmarking, piloting, and evaluating existing and emerging devices for data collection.

“We are delighted that the NIHR has chosen to award £4.5m to South London and Maudsley. It will fund equipment for our new Pears Maudsley Centre for Children and Young People to enable our academics and clinicians to continue their world-leading research into the prevention and treatment of mental illness.”

David Bradley

Chief Executive Officer, South London and Maudsley NHS Foundation Trust

“This investment will allow us to purchase equipment, technology and hardware, across the NIHR Maudsley BRC, NIHR King’s CRF and for the Pears Maudsley Centre. Not only will this enhance our research capacity and capability, it will also improve the experience of participants in research, particularly children and people with mental health conditions, because our facilities have been designed with their needs in mind.  We are delighted that our application was considered excellent by the NIHR committee.”

Professor Matthew Hotopf

CBE FRCPsych FMedSci, Director of the NIHR Maudsley BRC, and Vice Dean (Research), Institute of Psychiatry, Psychology & Neuroscience, King’s College London

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Meet the Team: Southwark CWP Team

Meet the Team: Southwark CWP Team

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Meet the Team: Southwark CWP Team

The Children and young people’s Wellbeing Practioners (CWP) Programme spans across all the four community boroughs served by the South London and Maudsley Trust (Southwark, Lambeth, Lewisham, and Croydon).  The aims of the programme include providing a service to young people, parents and carers with close links to the local community, with focus on prevention and early intervention and to increase accessibility and see young people who might not meet the threshold for current CAMHS provision.

Felicia Oshin

Felicia Oshin

Children's Wellbeing Practitioner

Who are the Southwark CWP Team?

Children and young people’s Wellbeing Practitioners (CWP) for Southwark. We are an early intervention team who see parents of children and YP who might need some support with their mental health. Being an early intervention team, we aim to see young people and support them at an early stage to provide preventative support.

What interventions do the team offer?

We offer access to Guided self-help interventions which are eight sessions based on Cognitive Behavioural therapy principles, otherwise known as CBT. We do this by offering some education about what the difficulties are, introducing new ideas and arrange powerful coping strategies and also creating a staying well plan. These sessions will be collaborative between yourselves and your CWP, working together to help reduce the concerns. We hope to leave parents and young people with a toolbox of methods to help them.

Can CBT help with anxiety?

CBT sessions can be done on a 1-2-1 basis, but we can also offer workshops to support groups of parents or young people. Workshop topics cover areas such as how to deal with exam stress, managing anxiety relating to the pandemic, managing anxiety relating to transiting from primary school to secondary school, GCSES or A levels, and also a healthy self-esteem.

How can CWP support young people?

If you are aged between 12 to 18, the focus will be to meet with you rather than your parents. We can help with worries, or fears that are getting in the way of their day-to-day life, for example worries about academic performance, health, or social relationships.

We also see young people who are feeling low and unmotivated which may have had an impact on their sleep, activities, relationships or school and it may result in constant feelings of sadness.

Do you support parents too?

Yes! We see parents of children between the age of 5 and 11 years who’s fears or worries are starting to affect their daily lives. As well as parents with children aged between 5 and 8 years old who would like help on how to respond to their children’s behaviour such as temper tantrum or difficulties following rules.

What other workshops do you offer?

 Alongside support with managing anxiety, we offer.

      • Self-esteem // body image / social media (for secondary school aged children)
      • Transitions (For Year 6, Year 7 or Year 11/12)
      • Low mood (Secondary School age)
      • Emotional regulation (for parents) Exam stress (Any secondary school year but most helpful for those doing GCSEs or A levels)

 How can young people or parents access support?

 If you would like to access support from Southwark CWP Services, talk to your local Children’s centre, GP, a member of school or college or professional in the community. Let them know you would like to access support from the Southwark CWP services, they will then make a referral to our service. Once we have received the referral, we will be in touch. Or you can access the referral form from our website.

Remember everyone deserves to be the best version of themselves and it is okay to not feel like it sometimes. We really look forward to working with you and we hope we can work together to support you.

For more information on the Southwark CWP Service, visit https://slam.nhs.uk/southwark-cwp

 

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IoPPN researchers awarded Wellcome funding for mental health research

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IoPPN researchers awarded Wellcome funding for mental health research
£2.45 million Wellcome funding has been awarded to research programmes at the Institute of Psychiatry, Psychology & Neuroscience (IoPPN) for children and young people’s mental health research.

The programme, led by IoPPN principal investigator Dr Daniel Michelson a received Wellcome Mental Health Award, alongside two other programmes at the IoPPN. The awards sit under the umbrella of Wellcome’s new Mental Health Challenge programme.

Dr Daniel Michelson has been awarded £2.45 million to undertake a ‘Mechanistic trial of problem-solving and behavioural activation for youth depression’ (METROPOLIS). This programme, which is part of the King’s Maudsley Partnership for Children and Young People, will investigate the effectiveness and mechanisms of brief, first-line psychotherapies to reduce symptoms of depression among disadvantaged university students in New Delhi, incorporating an innovative peer-to-peer counselling approach.

I’m delighted to receive this award on behalf of an outstanding international team. The funding will enable us to conduct one of the largest-ever mental health intervention trials for young people in India, which is home to 20% of all 18-24-year-olds worldwide. Scalable early interventions are urgently needed during this key developmental period when many mental health problems first occur. University settings pose unique challenges and stresses, especially for ‘first-generation’ learners who make up a significant part of the student population across India.

Dr Daniel Michelson

Clinical Senior Lecturer at the Department of Child and Adolescent Psychiatry, Institute of Psychiatry, Psychology & Neuroscience (IoPPN)

Dr Michelson is a Clinical Senior Lecturer in the Department of Child and Adolescent Psychiatry at the IoPPN. The new Award builds on Dr Michelson’s experience as Clinical Academic Director for the ‘Premium for Adolescents’ school mental health programme in India, also funded by Wellcome (2016-22). Dr Michelson additionally works on developing and evaluating psychosocial interventions for under-served children, young people and families in the UK and is an Honorary Consultant Clinical Psychologist at South London and Maudsley NHS Foundation Trust.

Daniel Stahl, Professor of Medical Statistics and Statistical Learning at the IoPPN, will work with Dr Michelson on the programme alongside co-investigators from Sangath, India’s leading mental health research non-governmental organisation; O.P. Jindal Global University, a top-ranked research-intensive university in New Delhi; Youth for Mental Health, a youth-led social enterprise focused on student mental health in India; and Brighton and Sussex Medical School. Dr Michelson’s team is supported by a wider group of international collaborators from the USA (Harvard Medical School, Loma Linda University & UCLA) and India (the National Institute of Mental Health and Neurosciences).

Young people with relevant lived experience will be front and centre in the leadership and delivery of the programme, including a variety of youth-led activities to engage students from marginalised groups.

Dr Daniel Michelson

Clinical Senior Lecturer at the Department of Child and Adolescent Psychiatry, Institute of Psychiatry, Psychology & Neuroscience (IoPPN)

The grant is funded under the Wellcome ’Looking Backwards, Moving Forward: understanding how interventions for anxiety, depression, and psychosis work’ grant scheme which is part of their new strategic focus on mental health as a key global health challenge. This call focuses on investigating the causal mechanisms underpinning the ‘active ingredients’ of effective interventions for anxiety, depression and psychosis. Active ingredients are those that drive resolution or reduction of symptoms, are well-defined and link to specific hypothesised mechanisms of action. Wellcome have awarded more than £47 million to research teams to investigate what makes interventions for anxiety, depression and psychosis effective.

For more information, please contact Amelia Remmington (Communications & Engagement Officer).

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New Executive Dean of the IoPPN

New Executive Dean of the IoPPN

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New Executive Dean of the IoPPN

Professor Matthew Hotopf CBE has been appointed as Executive Dean of the Institute of Psychiatry, Psychology and Neuroscience (IoPPN) from 1 September 2023.

a young girl holding a leaf

Professor Hotopf is a Professor of General Hospital Psychiatry, a consultant liaison psychiatrist, and Director of The National Institute for Health and Care Research (NIHR) Maudsley Biomedical Research Centre (BRC).

As an alumnus of King’s College London, Professor Hotopf has a rich history with the university as a student and a valued member of staff. Matthew joined King’s as a Senior Lecturer in Psychiatry at Guy’s King’s and St Thomas’ School of Medicine in 1998, establishing an eminent career which includes roles within King’s Health Partners (KHP) and at the IoPPN. He has held his current role of Vice Dean of Research at the IoPPN, since 2017 and led the IoPPN’s return to the Research Excellence Framework (REF) 2021.

“Matthew has demonstrated outstanding leadership and successful delivery of critical projects for King’s, such as REF2021 for the IoPPN and the Directorship and renewal of the NIHR Maudsley Biomedical Research Centre. He is an exemplar at managing complex partnerships across research, healthcare services, policy, industry, funding and clinical care. Matthew is a great motivator, encouraging both staff and students to fulfil their potential. I am looking forward to Matthew leading the IoPPN into its next chapter.” – Professor Shitij Kapur, President & Principal of King’s College London.

David Bradley, Chief Executive of South London and Maudsley NHS Foundation Trust, said:  “I am delighted that Professor Matthew Hotopf, CBE, has been appointed as Executive Dean of IoPPN. Matthew is bringing a wealth of experience across research, leadership, and educational skills. I know his experience will help us improve our services at South London and Maudsley and his leadership at IoPPN will make a hugely positive contribution to our work.” 

Matthew trained in epidemiology at the London School of Hygiene and Tropical Medicine and in Psychiatry at the Maudsley. He has broad research interests including using epidemiological and novel mobile health methods to interrogate the relationship between mental and physical health. He has a national research profile as a member of the REF and inaugural chair of the NIHR’s Translational Research Collaboration in Mental Health.

“It is a huge honour to be appointed as Executive Dean of IoPPN. There are many great opportunities ahead for us to advance neuroscience and mental health, and inspire the next generation through our education, training and research.” – Professor Matthew Hotopf CBE, Vice Dean of Research, Institute of Psychiatry, Psychology & Neuroscience (IoPPN)

Matthew’s awards include a CBE for services to Psychiatric Research in June 2018 and the Academy of Psychosomatic Medicine’s 2016 Wayne Katon Research Award. He is also a NIHR Senior Investigator and Fellow of the Academy of Medical Sciences.

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Maudsley Hospital: Celebrating 100 years

Maudsley Hospital: Celebrating 100 years

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Celebrating 100 years

This month the South London and Maudsley are celebrating Maudsley Hospital which opened to the public 100 years ago today.

a young girl holding a leaf

The hospital had first been requisitioned by the War Office before its completion in 1915 to deal with the military casualties of the First World War. Their organisation has changed in many ways over the last century, but thanks to their staff and partners, Henry Maudsley’s vision, of a hospital in an urban centre where mental healthcare, teaching and research would come together, endures.

A vision we intend to continue and develop when the Pears Maudsley Centre for Children and Young People opens next year.

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